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Acrylamide in coffee: Estimation of exposure from vending machines

机译:咖啡中的丙烯酰胺:自动售货机的暴露量估算

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摘要

The present study aimed to evaluate the levels of acrylamide in coffee brews acquired from coffee vending machines. Acrylamide content ranged from 7.7 to 40.0 μg/L (mean: 20.6 μg/L). These levels are similar to those found in coffee brews prepared by other coffee machines with different extraction procedures. The dietary exposure of the Spanish population to acrylamide through coffee drinks was estimated at 0.037 μg/kg body weight/day (range 0.018–0.056 μg/kg body weight/day). The maximum acrylamide exposure is lower than the value of 0.2 mg/kg body weight/day, defined as the lowest no observed adverse effect level (NOAEL) for a non-carcinogenic end-point. Therefore it may be suggested that exposure to acrylamide through vending machine coffees does not imply a high risk to public health. These data are useful to the different stakeholders involved in risk assessment, and in general to risk communicators, policy makers and the industry.\udChemical compounds described in this article: acrylamide (PubChem CID: 6579); potassium hexacyanoferrate(II) trihydrate (PubChem CID: 161067); zinc acetate dehydrate (PubChem CID: 2724192); methanol (PubChem CID: 887); formic acid (PubChem CID: 284).
机译:本研究旨在评估从咖啡自动售货机购得的咖啡冲泡物中的丙烯酰胺含量。丙烯酰胺含量范围为7.7至40.0μg/ L(平均值:20.6μg/ L)。这些水平与其他咖啡机采用不同提取程序制备的咖啡冲泡中的含量相似。据估计,西班牙人通过咖啡饮料对丙烯酰胺的饮食暴露为0.037μg/ kg体重/天(范围为0.018-0.056μg/ kg体重/天)。丙烯酰胺的最大暴露量低于0.2 mg / kg体重/天的值,该值定义为非致癌终点的最低未观察到不良反应水平(NOAEL)。因此,可以建议通过自动售卖机咖啡接触丙烯酰胺并不意味着对公共健康的高风险。这些数据对于参与风险评估的不同利益相关者很有用,并且对于风险传达者,政策制定者和整个行业都是有用的。\ ud本文描述的化合物:丙烯酰胺(PubChem CID:6579);三水合六氰合铁酸钾(II)(PubChem CID:161067);脱水醋酸锌(PubChem CID:2724192);甲醇(PubChem CID:887);甲酸(PubChem CID:284)。

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